JIDAM
"An Official Journal of IDA - Madras
Branch" ©2019.
Available online
Hyaluronic acid (also known as hyaluronan or hyaluronate) is naturally found linear polysaccharide in many tissues and fluids, but more abundantly in articular cartilage and synovial fluid (SF). It is a large non-sulphated glycosaminoglycan that is an important component of extracellular matrix (ECM) and a biodegradable polymer. Due to a variation in its molecular weight, HA derivatives can be utilized to make different formulations like fillers, creams, gels, and drops. HA-based drug research has seen a recent surge largely due to some properties like mucoadhesion, biocompatibility, and ease of chemical modification. Hyaluronic acid (HA) content varies widely in different joints and species. HA is a non-sulphated, naturally occurring non-protein glycosaminoglycan (GAG), with distinct physico-chemical properties, produced by synoviocytes, fibroblasts, and chondrocytes. It has a wide effect in clinical uses in a different field. In the field of dentistry due to its effective properties, it has various clinical uses in Periodontics.
Key words: hyaluronic acid, properties, clinical uses in periodontics
JIDAM/Volume:10/Issue:4/October - December 2023